Description
Product Characteristics:
DPF1 is a 353 amino acid protein that contains two PHD-type zinc fingers and belongs to the requiem/DPF family. Localized to both the nucleus and the cytoplasm, DPF1 is thought to play an important role in the regulation of neuronal cell survival. Specifically, DPF1 may function as a neurospecific transcription factor that binds DNA and participates in cell cycle progression. Human and rat DPF1 share 93 % sequence identity, suggesting a conserved role between species. Multiple isoforms of DPF1 exist due to alternative splicing events.
Subcellular location: Cytoplasm, Nucleus
Synonyms: NeuroD4, BAF45B, BRG1-associated factor 45B, D4, DPF1, DPF 1, DPF=1, DPF1_HUMAN, NEUD4, NEUD 4, Zinc and double PHD fingers family 1, Zinc finger protein neuro-d4.
Target Information: neurospecific gene that is developmentally regulated [RGD, Feb 2006]